Name: GENOMIC TOOLS IN RESEARCH
Code: 203301002
Type: Elective
ECTS: 4
Length of subject: Per term
Semester and course: 1st Year - First term
Speciality:
Language: English
Mode of study: On-site class
Lecturer data: EGEA GUTIÉRREZ-CORTINES, MARCOS
Knowledge area: Genética
Department: Ingeniería Agronómica
Telephone: 868071077 - 968325705 - 868071075
Email: marcos.egea@upct.es
Office hours and location:
Qualifications/Degrees:
PhD in Life Sciences from Ben-Gurion University of the Negev (ISRAEL) - 1992
Academic rank in UPCT: Catedrático de Universidad
Number of five-year periods: 6
Number of six-year periods: 4 de investigación y 1 de transferencia
Curriculum Vitae: Full Profile
Lecturer data: WEISS , JULIA ROSL
Knowledge area: Genética
Department: Ingeniería Agronómica
Telephone: 968325777
Email: julia.weiss@upct.es
Office hours and location:
miércoles - 13:00 / 17:00
EDIFICIO DE ETSI AGRONÓMICA, planta 2, Despacho 2.15
Se ruega contactar previamente por correo electrónico indicando emotivo de la tutoría.
Qualifications/Degrees:
Academic rank in UPCT: Catedrática de Universidad
Number of five-year periods: 4
Number of six-year periods: 4 de investigación y 1 de transferencia
Curriculum Vitae: Full Profile
[CB6 ]. To possess and understand knowledge that provides a basis or opportunity to be original in the development and / or application of ideas, often in a research context.
[CG1 ]. To learn about the field of study in which agricultural and food research and development are developed and the research skills and methods related to such field.
[CG4 ]. To be able to perform a critical analysis, and an evaluation and synthesis analysis of new and complex ideas in the agri-food sector.
[CE1 ]. To synthesize previous knowledge together with newly acquired knowledge in the matter, so as to be able to cope in agri-food contexts in which there is little specific information.
[CE3 ]. To show a certain degree of scientific and technical training to start a research activity in the field of agri-food.
[CE4 ]. To show a certain degree of understanding of the concepts, principles and theories related to the chosen subjects of the master's program.
Competencias específicas de la asignatura:
1. Describir la estructura de genomas y métodos de análisis.
2. Manejar, a nivel de usuario principiante, programas bioinformáticos para búsqueda de secuencias en bases de datos. Programas Clustal X, BLAST y NJPLOT.
3. Describir los conceptos básicos de filogenética.
Aspectos referidos a la semipresencialidad:
Los estudiantes pueden participar en las actividades formativas de esta asignatura de forma presencial (acudiendo físicamente al espacio en el que se desarrollan) o en línea a través de internet, excepto en "Sesiones Prácticas de laboratorio, campo o planta piloto" en las que solo puede participarse de forma presencial.
[CT1 ]. Spoken and written effective communication
[CT4 ]. Using information resources responsibly
1.- Utilizar el método más adecuado para comunicar ideas, conclusiones o resultados, a una audiencia especializada o no, en contextos nacionales e internacionales.
2.- Localizar, analizar y seleccionar la información precisa para desarrollar su actividad profesional/investigadora.
1.- Estructura de los genomas. 2.- Genómica física. 3.- Procesos de activación y silenciamiento del genoma. Factores de transcripción y epigenética. 4.- Análisis transcriptómico y genómica funcional. 5.- Técnicas de ganancia y pérdida de función. Abordajes masivos. 6.- Evolución de genomas.
1. Genome structure 2. DNA and chromosome structure 3. DNA structure 4. Second and third generation sequencing technology 5. Plant and animal genomes 6. Transcription and functional genomics 7. Epigenetics 8. Transcriptomic analysis 9. Genome egimeering technologies
Databases. NCBI, SOLGENOMICS, JGI
Phylogenies
Making constructs of RNAI and CRISPR/Cas
Promoting the continuous improvement of working and study conditions of the entire university community is one the basic principles and goals of the Universidad Politécnica de Cartagena. Such commitment to prevention and the responsibilities arising from it concern all realms of the university: governing bodies, management team, teaching and research staff, administrative and service staff and students. The UPCT Service of Occupational Hazards (Servicio de Prevención de Riesgos Laborales de la UPCT) has published a "Risk Prevention Manual for new students" (Manual de acogida al estudiante en materia de prevención de riesgos), which may be downloaded from the e-learning platform ("Aula Virtual"), with instructions and recommendations on how to act properly, from the point of view of prevention (safety, ergonomics, etc.), when developing any type of activity at the University. You will also find recommendations on how to proceed in an emergency or if an incident occurs. Particularly when carrying out training practices in laboratories, workshops or field work, you must follow all your teacher's instructions, because he/she is the person responsible for your safety and health during practice performance. Feel free to ask any questions you may have and do not put your safety or that of your classmates at risk.
Class in conventional classroom: theory, problems, case studies, seminars, etc
Lectures in gemonics, transcriptomics and proteomics. Paper research. Bibliographic handling.
28
100
Class in laboratory: practical classes / internships
Development of a genomics project
2
100
Class in the field or open classroom (technical visits, lectures, etc.). In general, activities that require special resources or planning
Development of a genomics project
Oral presentation and attendance to other presentations
2
100
Class in a computer classroom: practical classes / internships
Bioinformatics at user level. USe of standard software for DNA and RNA research
6
100
Assessment activities (continuous assessment system)
Completing the tutorials and other aspects related
2
100
Assessment activities (final assessment system)
Multiple choice test
1
100
Tutorials
Tutorials. Problem and question solving. Online or in the lab/office
6
50
Student work: study or individual or group work
preparing oral presentation
Learning subject, reading papers, acquiring Genomics vocabulary
73
0
Individual test (oral or written)
Multiple choice test. a minimum of 7 to pass
25 %
Evaluation of practical sessions, visits and seminars based on reports and corresponding documents
depending on year we will do a deliverable of bioinformatics
20 %
Solving of cases, theoretical questions, practical exercises or problems given by the teaching staff
Evaluation redundant with he previous one
20 %
Presentation and defence of individual or group assignments (it may include auto-evaluation and peer-evaluation)
Oral presentation on research in genomics
30 %
Attendance to seminars and visits to companies
Depending on year it will be evaluated
0 %
Other evaluation activities
Short reports of Bioinformatic practicum
5 %
Individual test (oral or written)
multiple choice test minimum 7 to pass
45 %
Presentation and defence of individual or group assignments (it may include auto-evaluation and peer-evaluation)
oral presentation of work
35 %
Other evaluation activities
Short reports of Bioinformatic practicum
20 %
Author: Rashidi, Hooman
Title: Bioinformatics basics applications in biological science and medicine
Editorial: CRC Press
Publication Date: 2000
ISBN: 0849323754
Author: Bergeron, Bryan
Title: Bioinformatics computing
Editorial: Prentice Hall
Publication Date: 2003
ISBN: 0131008250
Author: , Ouellette, B.F. Francis
Title: Bioinformatics a practical guide to the analysis of genes and proteins
Editorial: Joh Wiley & Sons
Publication Date: 2015
ISBN: 9780585240879
Author:
Title: Nature
Editorial: Macmillan Journals ltd., etc.
Publication Date: 1869
ISBN:
Author: Knudsen, Steen
Title: Biologist's guide to analysis of DNA microarray data
Editorial: John Wiley & Sons
Publication Date: 2002
ISBN: 0471224901
Author: Brown, T.A.
Title: Genomes
Editorial: Wiley-Liss
Publication Date: 1999
ISBN: 0471316180
Author: Kahl, Günter
Title: The dictionary of gene technology genomics, transcriptomics, proteomics
Editorial: Wiley-VCH
Publication Date: 2001
ISBN: 3527301003
Author: Graur, Dan
Title: Fundamentals of molecular evolution
Editorial: Sinauer Associates
Publication Date: 2000
ISBN: 0878932666
Author: Page, Roderic D.M.
Title: Molecular evolution a phylogenetic aprroach
Editorial: Blackwell
Publication Date: 2000
ISBN: 0865428891
Author: Schena, Mark
Title: Microarray biochip technology
Editorial: Eaton
Publication Date: 2000
ISBN: 1881299376